PPAR: A Pivotal Regulator in Metabolic Syndromes

نویسندگان

چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

PPAR: A Pivotal Regulator in Metabolic Syndromes

Copyright: © 2012 Fei J. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Peroxisome Proliferator-Activated Receptor (PPAR) includes three isoforms: PPARα, PPARβ/δ and PPARγ. They are transcription factors acti...

متن کامل

PPAR-: A master metabolic nuclear receptor

Peroxisome proliferator-activated receptor-γ (PPAR-γ) is a member of metabolic nuclear receptors called PPARs, which regulate all facets of the fatty acid metabolism including transport, synthesis, storage, mobilization, activation and oxidation of fatty acids. Hence, this receptor could be a drug target for metabolic syndrome-related noncommunicable diseases (NCD) like obesity, diabetes, cardi...

متن کامل

Seminal CD38 is a pivotal regulator for fetomaternal tolerance.

A successful pregnancy depends on a complex process that establishes fetomaternal tolerance. Seminal plasma is known to induce maternal immune tolerance to paternal alloantigens, but the seminal factors that regulate maternal immunity have yet to be characterized. Here, we show that a soluble form of CD38 (sCD38) released from seminal vesicles to the seminal plasma plays a crucial role in induc...

متن کامل

Effects of Memantine, an NMDA Antagonist, on Metabolic Syndromes in Female NMRI Mice

Introduction: The brain glutamate neurotransmitter system and its NMDA receptors in the nucleus accumbens play an important role in the incidence of the phenomena of sensitivity and addiction. The present study examined the inhibitory effect of glutamate NMDA receptors in the nucleus accumbens in response to chronic stress. Methods: After the unilateral and bilateral cannula placement in the ...

متن کامل

PPAR ligands: potential therapies for metabolic syndrome.

Metabolic syndrome (MS), a condition characterized by multiple related clinical disorders including insulin resistance, central obesity, hyperlipidemia, hypertension, and heart disease, is an increasingly prevalent disease in industrialized societies. The intense research interest in the peroxisome proliferator-activated receptors (PPARs), by both the pharmaceutical industry and academia, stems...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Endocrinology & Metabolic Syndrome

سال: 2012

ISSN: 2161-1017

DOI: 10.4172/2161-1017.1000e113